• Slimming Products
    • Fatfix
    • Slimberry
    • Piperine Forte
    • Slimjoy
    • Slimy Liquid
    • Revolyn Keto Burn
    • Keto Tropfen
    • Reduslim
    • Vitalrin
    • Ultra Rev
    • Keto Guru
    • Purosalin
    • Slim XR
    • Vanefist Neo
    • Herzolex Ultra
    • Sliminazer
    • Idealica
    • Black Latte
    • GC Rocket
    • Formoline L112
    • Panaslim
    • Refigura
    • Slimymed
    • Ultra Keto Slim
  • Painkiller
    • Jointfuel360
    • Hondrostrong
    • Arthrolon
    • Flexa Plus Optima
    • Sustafix
    • Flexumgel
  • Reviews
    • Testonyl
    • Parazitol
    • Detonic
    • Sarahs Blessing
    • Recardio
    • Cardiline
    • Mindinsole
    • Detoxic
    • Nuubu
    • Viscerex
    • Nutresin
    • Rezilin
  • Guides
  • Potency Funds
    • Maral Gel
    • Eroxel
    • Maxatin
    • Urotrin
    • Viarax
    • Viraxol
    • Erogen X
    • Collosel
    • Potencialex
    • Phallosan Forte
  • Beauty
    • Veona
    • Varicofix
    • Vibrosculpt
    • Varikosette
  • Foot Care
    • Onycosolve
    • Fungonis Gel
    • Micinorm
  • Home
  • Uncategorized
  • Diabetes Drug Metformin May Lower Risk of Pancreatic Cancer for Women
  • 29. October 2020
  • 0 comments
  • Maria Bauer
  • Uncategorized

Diabetes Drug Metformin May Lower Risk of Pancreatic Cancer for Women

Increasing evidence is suggesting that Type 2 diabetes and pancreatic cancer are somehow linked, but exactly how the link works remains unclear.

A new study may help clarify things — it shows that taking a drug aimed at treating Type 2 diabetes may change a person’s risk of developing pancreatic cancer, depending on the drug.

Though some research has shown those with Type 2 diabetes are at an increased risk of developing pancreatic cancer, the new study found that women who took metformin, now the most common treatment for Type 2 diabetes, had a lower risk of pancreatic cancer than the general population. In contrast, women who took drugs from an older class of diabetes treatments, called sulfonylureas, had a higher risk of the cancer, according to the study.

For men, insulin use was linked with a slightly increased risk of pancreatic cancer.

The gender differences surprised the scientists at the University of Basel in Switzerland, who conducted the research. “This result is somewhat unexpected, and could not be explained by confounding use of estrogens,” they wrote in the paper, which was published Jan. 31 in the American Journal of Gastroenterology.

Previous, smaller studies have found decreased risk of pancreatic cancer in people taking metformin, but the results of those studies did not consider the genders separately.

Diabetes and pancreatic cancer

About 26 million people in the U.S. have Type 2 diabetes, and that number could double or even triple over the coming decades, according to the Centers for Disease Control and Prevention.

Previous work has reported an overall increased risk of pancreatic cancer in diabetes patients, and researchers have suggested that, among risk factors that are affected by a person’s behavior, having Type 2 diabetes is the third most important risk factor for pancreatic cancer, behind smoking and obesity.

Metformin has been linked with a decreased risk of breast and ovarian cancers in other studies.

In the new study, researchers turned to a database of patient records in the U.K. to look at the drug’s association with pancreatic cancer. They analyzed patient histories, including prescriptions, diagnoses of cancer and diabetes, and records of smoking and alcohol consumption.

The team based their findings on the records of 2,763 patients eventually diagnosed with pancreatic cancer and 16,578 control participants from the general population who didn’t have the cancer, but were matched to the study participants in terms of their age and other factors.

Overall, the researchers found no link between metformin use and pancreatic cancer. However, when they looked at each gender separately, they found that women who developed pancreatic cancer were half as likely to have taken metformin for at least three years compared with women who didn’t have pancreatic cancer.

On the other hand, women with pancreatic cancer were three times as likely to have taken sulfonylureas for at least three years compared with those who didn’t have pancreatic cancer.

The link between diabetes itself and pancreatic cancer is one that’s been hard to sort out, said Dr. Christopher Forsmark, a gastroenterologist at the University of Florida College of Medicine and previous president of the American Pancreatic Association.

“There’s a curious connection between Type 2 diabetes and pancreatic cancer,” said Forsmark, who was not involved with the new study. “A lot of people who get pancreatic cancer develop diabetes at the time they get the cancer. But there’s also some data that folks who had long-standing diabetes might have a somewhat increased risk of getting pancreatic cancer.”

Still, the new study found that the overall rates of pancreatic cancer were similar for those who had diabetes and those who didn’t.

Targeting metabolic syndrome

Forsmark said that the differing effects of the diabetes drugs on pancreatic cancer risk could lie in the fact that metformin treats a more underlying cause of diabetes. Fat cells throughout the body secrete a variety of chemicals into the body that may promote cancer growth, and metformin aims to treat diabetes by targeting these cells, rather than by simply increasing the body’s insulin levels, as other drugs do.

But more work is needed to better understand the connection between diabetes and pancreatic cancer.

The slight changes in pancreatic cancer risk seen in this study are not large enough to change the way doctors treat diabetes, Forsmark said.

Most diabetic patients, he added, have a much higher chance of developing complications from high blood sugar and untreated metabolic syndrome than they have of developing pancreatic cancer.

Pass it on: A new study suggests that treating an underlying cause of Type 2 diabetes may lower pancreatic cancer risk for women.

Follow MyHealthNewsDaily on Twitter @MyHealth_MHND. 

  • 10 Do’s and Don’ts to Reduce Your Risk of Cancer
  • Why Is Pancreatic Cancer So Deadly?
  • 7 Cancers You Can Ward Off with Exercise
Maria-Cakehealth
Maria Bauer

Maria is our expert for medicine, fitness and general health. Her contributions are particularly convincing through completeness, accuracy and her own personal experience. Maria also writes for other health magazines, which has enabled her to build up her expert status.

Leave Comment

or cancel reply

Suche
Beliebte Beiträge
  • 7 Ways Alcohol Affects Your Health
    • 18. February 2021
    • 0
  • For Women, Sex May Be Improved by ‘Mindfulness Meditation’
    • 18. February 2021
    • 0
  • Autistic Brain Excels at Recognizing Patterns
    • 9. February 2021
    • 0
  • Swine Flu May Cause Baldness
    • 9. February 2021
    • 0
  • Dogs’ Contagious Cancer Cells May Survive By Theft
    • 9. February 2021
    • 0
  • Are You Sitting Down? If You’re a College Senior, Probably
    • 9. February 2021
    • 0
  • New Test May Screen Donated Blood for Fatal Disease-Causing Proteins
    • 9. February 2021
    • 0
  • Exercise Can’t Undo the Damage of Too Much Screen Time
    • 9. February 2021
    • 0
  • Melanoma Drug Shrinks Tumors, Study Finds
    • 9. February 2021
    • 0
  • Co-Conspirator Cells Contribute to Skin Cancer
    • 9. February 2021
    • 0
  • YouTube May Help Elderly Dementia Patients
    • 9. February 2021
    • 0
  • Brain Functioning Decline Higher in Southern ‘Stroke Belt’
    • 9. February 2021
    • 0
  • 8 Tips for Healthy Aging
    • 9. February 2021
    • 0
  • Alzheimer’s Vs. Normal Aging: How to Tell the Difference
    • 9. February 2021
    • 0
  • Soy Compounds May Cut Risk of Some Breast Cancers
    • 9. February 2021
    • 0
  • Estrogen May Curb Breast Cancer As Well As Promote It
    • 9. February 2021
    • 0
  • Flu Season Worse Than Usual
    • 9. February 2021
    • 0
  • Most Young Flu Victims Had Not Been Vaccinated, Fatality Report Says
    • 9. February 2021
    • 0
  • Indoor Tanners Use Beds Despite Boosting Skin Cancer Risk
    • 9. February 2021
    • 0
  • Gene Therapy May Ease Tremors in Parkinson’s Patients
    • 9. February 2021
    • 0
  • Alzheimer’s Often Misdiagnosed Until Later On
    • 9. February 2021
    • 0
  • In Trauma Patients, Steroids May Reduce Pneumonia Risk
    • 9. February 2021
    • 0
  • Will USDA’s New ‘Plate’ Icon Make a Difference in American Diets?
    • 9. February 2021
    • 0
  • Can Changing Your Diet Decrease Your Risk of Alzheimer’s?
    • 9. February 2021
    • 0
  • Preventive Measures Against Alzheimer’s Still Uncertain, Report Finds
    • 9. February 2021
    • 0
  • Exercise During Pregnancy Benefits Baby’s Heart
    • 9. February 2021
    • 0
  • Hypertension Death Rate Drops, But Fatalities Still High
    • 9. February 2021
    • 0
  • More Years of Schooling Have Healthful Effect on Blood Pressure
    • 9. February 2021
    • 0
  • Heavy Beer Drinkers Increase Their Gastric Cancer Risk
    • 9. February 2021
    • 0
  • Weight Gain: How Food Actually Puts on Pounds
    • 9. February 2021
    • 0
  • Want a Smaller Waist? Take More Breaks From Sitting
    • 9. February 2021
    • 0
  • New Rules on Vitamin D and Calcium: Most People Get Enough
    • 9. February 2021
    • 0
  • For Melanoma Patients, Arthritis Drug Could Treat Disease
    • 9. February 2021
    • 0
  • Brain Overgrowth in Tots Is Linked to Autism
    • 9. February 2021
    • 0
  • Airborne Mad Cow Disease Possible, But Unlikely
    • 9. February 2021
    • 0
  • Most High School Kids Don’t Get Enough Exercise, CDC Reports
    • 9. February 2021
    • 0
  • Is the 17 Day Diet Just Another Weight-Loss Gimmick?
    • 9. February 2021
    • 0
  • Lead Exposure May Delay Puberty in Girls
    • 9. February 2021
    • 0
  • The Healthy Geezer: Does Mercury Cause Cancer?
    • 9. February 2021
    • 0
  • 11% of Infants Born Preterm Worldwide
    • 9. February 2021
    • 0
  • Severe Morning Sickness Linked to Preterm Births
    • 9. February 2021
    • 0
  • More Money and No Dad Could Mean Early Puberty in Girls
    • 9. February 2021
    • 0
  • Too Little or Too Much Sleep May Raise Heart, Stroke Risks
    • 8. February 2021
    • 0
  • Relapse Common for Teens Who Overcome Depression
    • 8. February 2021
    • 0
  • Repeated Miscarriages May Increase Women’s Heart Attack Risk
    • 8. February 2021
    • 0
  • Earlier Detection of Dangerous Ectopic Pregnancies Possible with New Marker
    • 8. February 2021
    • 0
  • It’s in the Blood: New Hope for Detecting Schizophrenia
    • 8. February 2021
    • 0
  • Alcohol Abuse May Lead to Marriage Postponement, Separation
    • 8. February 2021
    • 0
  • Marriage Trouble Could Mean Poor Sleep for Baby
    • 8. February 2021
    • 0
  • Weight-Loss Surgery May Improve Memory
    • 8. February 2021
    • 0

Copyright © 2020 by cakehealth.com

Impressum|Data Protection | Sitemap EN|Sitemap DE